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Angiosarcoma is a form of sarcoma that is considered a clinically highly variable cancer of the blood vessels. Angiosarcomas are relatively rare, comprising only 1 to 2 percent of sarcomas. The risk of recurrence depends on the stage of disease. The cancer is thought to be caused by exposure to Vinyl Chloride and other toxins.

Over 40 years ago, the U.S. Centers for Disease Control and Prevention (CDC) published an intensive study of the health dangers of a chemical plastics plant. The review determined vinyl chloride (VC) monomer was a causative agent of the deadly cancer Angiosarcoma.

Several subsequent studies over recent years have confirmed the association, and workers in the chemical and plastics field have seen first-hand the dangerous health consequences. VC is now universally considered to be a highly potent chemical carcinogen.

Vinyl chloride (VC) is manufactured exclusively for polymerization into polyvinyl chloride (PVC), a plastic used in various industries and capacities, such as construction, piping, packaging, wire and cable coatings, and transportation.

Vinyl chloride is also used as a combustion product in tobacco. The toxic products are also in household products such as flooring, water piping, videodiscs, and even credit cards. Global PVC production in 2002 was valued at approximately US$19 billion.

Reviews by the World Health Organization and the International Agency for Research on Cancer (IARC) have repeatedly warned that vinyl chloride is a human carcinogen. The U.S. Environmental Protection Agency (EPA) has echoed these concerns, though the chemical still causing widespread damage. Exposure to the toxic material can cause reactions that primarily target the liver, brain, and lungs.

Joe Lyon is a highly-rated Cincinnati Toxic Tort Attorney and catastrophic injury lawyer representing plaintiffs nationwide in a wide variety of civil litigation claims.

Vinyl Chloride Exposure Risks

Vinyl chloride exposure is associated with an increased risk of Angiosarcoma, as well as brain and lung cancers, lymphoma, and leukemia. There is also evidence that certain disorders, such as pneumoconiosis and excess fetal deaths, may be associated with exposure to the chemical.

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Joseph Lyon has 17 years of experience representing individuals in complex litigation matters. He has represented individuals in every state against many of the largest companies in the world.

The Firm focuses on single-event civil cases and class actions involving corporate neglect & fraud, toxic exposure, product defects & recalls, medical malpractice, and invasion of privacy.


The Firm offers contingency fees, advancing all costs of the litigation, and accepting the full financial risk, allowing our clients full access to the legal system while reducing the financial stress while they focus on their healthcare and financial needs.

VC Exposure in the Workplace

Workers constitute the population most heavily exposed to chemical toxins and physical agents. Exposure to high levels of VC at the workplace can result in an increased incidence of angiosarcoma.

A review of studies involving about 45,000 workers exposed to VC showed an increase in incidence of cancer. Health issues of the respiratory tract, digestive system, lymphatic, pharynx, cardiovascular system and colon and stomach were reported to show an increased incidence in one or more studies.

Angiosarcoma Cancer Clusters

In the 1970s, a cluster of cases of Angiosarcoma of the liver, a rare cancer, was detected among workers in a Kentucky chemical plant. Officials from the CDC’s Bureau of Epidemiology, the National Institute for Occupational Safety and Health, and the National Cancer Institute investigated the workplace and determined that the workers were all exposed to vinyl chloride had an increased rate of Angiosarcoma of the liver.

Four cases of Angiosarcoma of the liver were diagnosed among men working in the polyvinyl chloride polymerization section of a B.F. Goodrich plant. All four men had worked in the toxic conditions for at least 14 years prior to onset of illness.

Medical officials confirmed the existence of the outbreak, and also discovered pre-malignant lesions in other members of the factory workers heavily exposed to VC.

Publication of this report in 1974 resulted in a series of clinical investigations and studies. Since then, exposure to vinyl chloride has been known to be a major risk factor for the development of Angiosarcoma.

Vinyl Chloride Cancer Risks

The recognition of vinyl chloride as carcinogenic stimulated regulatory activity. Consequently, the plastics-manufacturing industry developed a process that reduced releases of VC, partially eliminating worker exposures.
However, even with stricter regulations on vinyl chloride in the workplace, the question of its health effects remains in the spotlight.

According to the U.S. Environmental Protection Agency data in 2012, there were 15 major and two area source PVC facilities in the United States. PVC plants in Kentucky, and Louisiana, still pollute the air with vinyl chloride. In 2014, companies reported releasing more than 500,000 pounds of VC, according to the EPA.

Angiosarcoma Lawsuits & PVC

  • In 2014, residents of McCullom Lake, Illinois, settled a lawsuit in which they claimed vinyl chloride from a nearby chemical plant bled into groundwater, and thereby caused a cluster of 33 brain tumors. The Illinois Environmental Protection Agency had worked with the company to clean up toxic chemicals on the site since 1991. The settlement comes after eight years of litigation against a subsidiary of Dow Chemical Co.
  • During the 1980s, General Tire workers in an Ashtabula, Ohio plant were exposed to large amounts of vinyl chloride, years after the government set strict exposure limits. Former workers of the PVC plant, owned by General Tire & Rubber Co., were diagnosed with Angiosarcoma, traced to the chemical exposure.
  • GenCorp, Inc., a major producer of polyvinyl chloride, was named in a conspiracy lawsuit in Lake Charles, Louisiana. Lawyers named a total of 32 vinyl chloride and PVC manufacturers. While attorneys requested GenCorp to disclose every case of cancer that occurred among former plant employees, the company claimed it has lost employee medical records. Lawyers allege that GenCorp and dozens of other chemical firms covered up evidence of vinyl chloride’s toxicity and influenced an industry-funded, nationwide worker-mortality report.

    Negligent PVC Manufacturers

    Thousands of people still work in PVC production and fabrication, making flooring, siding, medical equipment, electrical wiring, cables and other products. These workers may have a risk of illness associated with their workplace.

    In addition, former workers in the chemical plastics industry are likely to have been exposed to VC toxins and may have a claim against manufacturers and employers. Any victim of these occupational hazards may contact an attorney for possible legal assistance.

    Risk Factors of Angiosarcoma

    Angiosarcoma of the skin makes up the majority of angiosarcoma cases, usually found on the scalp and face. The most common primary origins for angiosarcomas to form is in the head and neck area, heart, bone, liver, spleen, and breast, frequently years after radiation and breast cancer surgery.

    Approximately 25 percent of angiosarcomas are found in deep tissue, and around 8 percent are found in breast tissue. Unlike most sarcomas, which travel via the bloodstream to other organs such as lung or liver, angiosarcomas often travel to lymph nodes.

    Factors that may increase your risk of sarcoma include:

    •    Inherited syndromes and genetic irregularities
    •    Previous radiation treatment for other cancers
    •    Chemical exposure—exposure to certain herbicides, arsenic and dioxins
    •    Vinyl chloride (a chemical used in making plastics) is a risk factor for developing sarcomas of the liver
    •    Arsenic has been linked to a type of liver sarcoma
    •    Exposure to herbicides at high doses (in farm settings) may cause cancer

    Age appears to play a factor as well. Studies show peak incidence is in the seventh decade of life.


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A Voice for Those who have suffered

Why are these cases important?

Rightful compensation for plaintiffs can recover sizable settlements and can help pay for mounting medical expenses and other damages that may include long-term disability, rehabilitation, pain and suffering and lost wages. During some of the toughest times in a family’s life, The Lyon Firm can be of assistance.

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Questions about Catastrophic Injury Cases

What is a Catastrophic Injury Lawsuit?

A lawsuit with severe and debilitating damages. In these cases, liability must be proven first. In many cases, the root cause of the injury is unknown and requires expert investigation.

Why should I hire The Lyon Firm?

Our Firm will help you find the answers.  The Firm has the experience, resources and dedication to take on difficult and emotional cases and help our clients obtain the justice for the wrong they have suffered. 

 Experience:  Joe Lyon is an experienced Cincinnati Catastrophic Injury Lawyer. The Lyon Firm has 17 years of experience and success representing individuals and plaintiffs in all fifty states, and in a variety of complex civil litigation matters. Catastrophic Injury lawsuits can be complex and require industry experts to determine the root cause of an accident or injury. Mr. Lyon has worked with experts nationwide to assist individuals understand why an injury occurred and what can be done to improve their lives in the future. Some cases may go to a jury trial, though many others can be settled out of court.

Resources/Dedication: Mr. Lyon has worked with experts in the fields of accident reconstruction, biomechanics, epidemiology, metallurgy, pharmacology, toxicology, human factors, workplace safety, life care planning, economics, and virtually every medical discipline in successfully representing Plaintiffs across numerous areas of law. The Lyon Firm is dedicated to building the strongest cases possible for clients and their critical interests.

Results:  Mr. Lyon has obtained numerous seven and six figure results in personal injury,  automotive product liability, medical Negligence, construction accidents, and auto dealership negligence cases.  The cases have involved successfully litigating against some of  the largest companies in the world 

How do you treat Angiosarcoma & Sarcoma?

Experts recommend that patients with sarcoma consult a team of doctors, possibly including orthopedic surgeons, oncologists, thoracic surgeons, and radiation specialists. Chemotherapy is standard, though there is no standard regimen after surgical removal of the tumor.

After a sarcoma is found, a treatment plan will be determined based on the type, location, and stage of the cancer, as well as a patient’s overall physical health. Treatment for soft tissue sarcomas include:

•    Surgery
•    Radiation
•    Chemotherapy
•    Targeted therapy (anti-angiogenic therapy)

All angiosarcomas tend to be aggressive, difficult to treat, and tend to recur locally, spread widely, and have a high rate of lymph node and systemic metastases. The rate of tumor-related death is high. The overall relative 5-year survival rate of people with soft tissue sarcomas is around 50 percent, according to the National Cancer Institute (NCI).

What are the symptoms of Angiosarcoma?

Symptoms that present will depend on where the cancer originated and if it has spread to other parts of the body. In its early stages, soft tissue sarcomas may not cause any signs and symptoms. However, as the tumor grows, it may cause noticeable lumps or swelling, and pain if the tumor presses on nerves or muscles.

The tumors may grow and spread in an irregular pattern near the surface of the skin, or as masses in soft tissue or other organs. Primary origins of Angiosarcoma commonly include the heart and breast. Approximately 50 percent of Angiosarcomas occur in the head and neck. Angiosarcomas also can originate in the liver, spleen, bone, or brain.

How are people exposed to Vinyl Chloride?

Workers at vinyl chloride facilities may be exposed primarily through inhalation. Outside production facilities, the highest levels of vinyl chloride are found in air around VC factories. Several cases of angiosarcoma have occurred in people living in the vicinity of VC plants. There is a possibility that low-level exposure to VC over a long period can cause serious illnesses.

Your Right to Justice

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Many of my clients come to me in the hardest moments of their lives. They’ve suffered catastrophic injury, they’ve lost a family member, their business has suffered a catastrophic loss that they may not be able to overcome.

It’s a fear of the future and uncertainty that has driven them to come to a lawyer and to ask, ‘What available legal rights are there?’ in order to add some security for their future. The Lyon Firm takes the lead and guides clients through the process of filing catastrophic injury lawsuits.

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